Publications
Brunquell , Jessica, et al. " HSF-1 is a regulator of miRNA expression in Caenorhabditis elegans. " Plos one 12.8 (2017): e0183445
Brunquell, J., S., Snyder, A., & Westerheide S.D. (2017). Cofee extract and caffeine enhances the heat shock response and promote proteostasis in HSF-1 dependent manner in Caenorhabditis elegans. Cell Stress and Chaperones., 1-11.
Jessica Brunquell, Stephanie Morris, Yin Lu, Feng Cheng, and Sandy D. Westerheide. The Genome-Wide Role of HSF-1 in the Regulation of Gene Expression in Caenorhabditis elegans. BMC Genomics. 2016 Aug 5.
Clare Edwards, John Canfield, Neil Copes, Muhammad Rehan, David Lipps, Jessica Brunquell, Sandy Westerheide and Patrick Bradshaw. Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 2015 Feb 3;16(1):8.
Jessica Brunquell, Sandy D. Westerheide, and Bin Xue. Evolution and disorder analyses show that DBC1/CCAR2 and CCAR1 have evolved from the nematode protein LST-3. BioMed Research International. 2014. 2014:418458.
Jessica Brunquell, Philip Bowers, and Sandy D. Westerheide. Fluorodeoxyuridine enhances the heat shock response and decreases polyglutamine aggregation in an HSF-1-dependent manner in Caenorhabditis elegans. Mechanisms of Ageing and Development. 2014. 141-142:1-4
Beate I. Escher, et al. Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays. Environ Sci Technol. Feb 2014. 48(3):1940-56
Joseph Foley, Shannon E. Hill, Tatiana Miti, Mentor Mulaj, Marissa Ciesla, Rhonda Robeel, Christopher Persichilli, Rachel Raynes, Sandy D. Westerheide and Martin Muschol. Structural Fingerprints of Intermediates Formed During Oligomeric vs. Oligomer-free Lysozyme Fibril Growth. Journal of Chemical Physics. 2013. 139(12):121901.
Rachel Raynes, Jessica Brunquell and Sandy D. Westerheide. Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer. Genes & Cancer. 2013. DOI: 10.1177/1947601913484497
Rachel Raynes, Kathleen M. Pombier, Kevin Nguyen, Jessica Brunquell, Jamie E. Mendez, and Sandy D. Westerheide. The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. PLOS ONE. 2013. 8(1): e54364
Rachel Raynes, Bruce Leckey, Kevin Nguyen and Sandy D. Westerheide. Heat Shock and Caloric Restriction have a Synergistic Effect on the Heat Shock Response in C. elegans. J Biol Chem. 2012. 287(34):29045
Sandy D. Westerheide, Rachel Raynes, Chase Powell, Bin Xue, and Vladimir N. Uversky. Characterization of HSF as an intrinsically disordered transcription factor family. Current Protein and Peptide Science. 2012. 13(1):86. Review.
Sandy D. Westerheide*, Julius Anckar*, Stanley Stevens, Lea Sistonen and Richard I. Morimoto. Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase S IRT1. Science, 2009. 323(5917):1063 *co-first authors
Richard I. Morimoto and Sandy D. Westerheide. The heat shock response and the stress of misfolded proteins in the Handbook of Cell Signaling. Ralph Bradshaw and Edward Dennis, editors. (Elsevier, Inc., San Diego, California). 2009.
Amy Trott, James D. West, Lada Klaic, Sandy D. Westerheide, Richard B. Silverman, Richard I. Morimoto and Kevin A. Morano. Simultaneous activation of heat shock and oxidative stress pathways by celastrol. Mol Biol Cell, 2008. 19(3):1104
Sandy D. Westerheide, Tiara L. Kawahara, Kai Orton and Richard I. Morimoto. Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death. J Biol Chem, 2006. 281(30):21575
Sandy D. Westerheide and Richard I. Morimoto. Heat shock modulators as therapeutic tools for diseases of protein conformation. J Biol Chem, 2005. 280(39):33097
Sandy D. Westerheide, Joshua D. Bosman, Bessie N. A. Mbadugha, Tiara L. A. Kawahara, Gen Matsumoto, Soojin Kim, Wenxin Gu, John P. Devlin, Richard B. Silverman, and Richard I. Morimoto. Celastrols as inducers of the heat shock response and cytoprotection. J Biol Chem, 2004. 279(53):56053
Brunquell, J., S., Snyder, A., & Westerheide S.D. (2017). Cofee extract and caffeine enhances the heat shock response and promote proteostasis in HSF-1 dependent manner in Caenorhabditis elegans. Cell Stress and Chaperones., 1-11.
Jessica Brunquell, Stephanie Morris, Yin Lu, Feng Cheng, and Sandy D. Westerheide. The Genome-Wide Role of HSF-1 in the Regulation of Gene Expression in Caenorhabditis elegans. BMC Genomics. 2016 Aug 5.
Clare Edwards, John Canfield, Neil Copes, Muhammad Rehan, David Lipps, Jessica Brunquell, Sandy Westerheide and Patrick Bradshaw. Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 2015 Feb 3;16(1):8.
Jessica Brunquell, Sandy D. Westerheide, and Bin Xue. Evolution and disorder analyses show that DBC1/CCAR2 and CCAR1 have evolved from the nematode protein LST-3. BioMed Research International. 2014. 2014:418458.
Jessica Brunquell, Philip Bowers, and Sandy D. Westerheide. Fluorodeoxyuridine enhances the heat shock response and decreases polyglutamine aggregation in an HSF-1-dependent manner in Caenorhabditis elegans. Mechanisms of Ageing and Development. 2014. 141-142:1-4
Beate I. Escher, et al. Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays. Environ Sci Technol. Feb 2014. 48(3):1940-56
Joseph Foley, Shannon E. Hill, Tatiana Miti, Mentor Mulaj, Marissa Ciesla, Rhonda Robeel, Christopher Persichilli, Rachel Raynes, Sandy D. Westerheide and Martin Muschol. Structural Fingerprints of Intermediates Formed During Oligomeric vs. Oligomer-free Lysozyme Fibril Growth. Journal of Chemical Physics. 2013. 139(12):121901.
Rachel Raynes, Jessica Brunquell and Sandy D. Westerheide. Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer. Genes & Cancer. 2013. DOI: 10.1177/1947601913484497
Rachel Raynes, Kathleen M. Pombier, Kevin Nguyen, Jessica Brunquell, Jamie E. Mendez, and Sandy D. Westerheide. The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. PLOS ONE. 2013. 8(1): e54364
Rachel Raynes, Bruce Leckey, Kevin Nguyen and Sandy D. Westerheide. Heat Shock and Caloric Restriction have a Synergistic Effect on the Heat Shock Response in C. elegans. J Biol Chem. 2012. 287(34):29045
Sandy D. Westerheide, Rachel Raynes, Chase Powell, Bin Xue, and Vladimir N. Uversky. Characterization of HSF as an intrinsically disordered transcription factor family. Current Protein and Peptide Science. 2012. 13(1):86. Review.
Sandy D. Westerheide*, Julius Anckar*, Stanley Stevens, Lea Sistonen and Richard I. Morimoto. Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase S IRT1. Science, 2009. 323(5917):1063 *co-first authors
Richard I. Morimoto and Sandy D. Westerheide. The heat shock response and the stress of misfolded proteins in the Handbook of Cell Signaling. Ralph Bradshaw and Edward Dennis, editors. (Elsevier, Inc., San Diego, California). 2009.
Amy Trott, James D. West, Lada Klaic, Sandy D. Westerheide, Richard B. Silverman, Richard I. Morimoto and Kevin A. Morano. Simultaneous activation of heat shock and oxidative stress pathways by celastrol. Mol Biol Cell, 2008. 19(3):1104
Sandy D. Westerheide, Tiara L. Kawahara, Kai Orton and Richard I. Morimoto. Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death. J Biol Chem, 2006. 281(30):21575
Sandy D. Westerheide and Richard I. Morimoto. Heat shock modulators as therapeutic tools for diseases of protein conformation. J Biol Chem, 2005. 280(39):33097
Sandy D. Westerheide, Joshua D. Bosman, Bessie N. A. Mbadugha, Tiara L. A. Kawahara, Gen Matsumoto, Soojin Kim, Wenxin Gu, John P. Devlin, Richard B. Silverman, and Richard I. Morimoto. Celastrols as inducers of the heat shock response and cytoprotection. J Biol Chem, 2004. 279(53):56053
